Validation of EPA Method 1633:

With Semi-Automated Solid Phase Extraction

Significant progress has been made in recent years in developing reliable tools for PFAS detection and analysis. Until a few years ago, the U.S. Environmental Protection Agency (EPA) had not yet established a standardized method for PFAS analysis in environmental samples such as groundwater, surface water, and soils. This led to inconsistencies across laboratories, each developing its own analytical approaches. The introduction of EPA Method 1633 has addressed these challenges by providing a validated, standardized protocol for detecting PFAS contaminants across multiple matrices.

Finalization of EPA Method 1633

In January 2024, the EPA finalized Method 1633, marking a crucial milestone in environmental analysis. This method now offers a comprehensive solution for measuring PFAS in diverse environmental samples, including:
✔ Groundwater, surface water, and wastewater
✔ Landfill leachate, soils, and sediments
✔ Biosolids and biological tissue

EZPFC® Semi-Automated SPE for Method 1633

To support the adoption of EPA Method 1633, FMS developed the EZPFC® Semi-Automated Solid Phase Extraction (SPE) system, offering a cost-effective and high-throughput approach to PFAS extraction. This system enhances laboratory efficiency by automating key sample preparation steps while ensuring high-quality, contamination-free results.

Key Benefits of EZPFC® for Method 1633

• Reliable & Standardized Workflow – Reduces inconsistencies in sample preparation
• High Sample Throughput – Increases processing efficiency for environmental labs
• Precision & Accuracy – Ensures optimal PFAS recovery with minimal contamination risk
• Cost-Effective Solution – Provides an affordable alternative to fully automated systems

With EPA Method 1633 now finalized, laboratories can confidently apply a validated, high-precision approach to PFAS testing. To explore key challenges in PFAS extraction, visit FMS’s Challenges in PFAS Extraction.

For more details on EPA Method 1633, access the official EPA publication.